What is the ANCA - PR3 (Serin Proteinase 3 antibodies) test?
This Proteinase-3 (PR-3) is a neutral serine proteinase present in azurophil granules of human polymorphonuclear leukocytes and serves as the major target antigen of antineutrophil cytoplasmic antibodies with a cytoplasmic staining pattern (c-ANCA) in Wegener's granulomatosis (WG).
When is the ANCA - PR3 (Serin Proteinase 3 antibodies) test recommended?
It is recommended:When symptoms of the disease such as fever, sinus pain, hearing loss, numbness, and chest pain appear.Depending upon the organ affected, there are different types of vasculitis conditions, such as granulomatosis with polyangiitis (lungs, kidneys, and sinuses), microscopic polyangiitis (lungs, kidneys, nervous system, and skin), eosinophilic granulomatosis with the polyangiitis (skin and lungs), and polyarteritis nodosa (heart, kidneys, skin, and central nervous system).
What does it measure?
The ANCA - PR3 (Serin Proteinase 3 antibodies) test: Detects and analyzes systemic autoimmune vasculitis and other autoimmune disorders such as Wegener's Granulomatosis (WG), Microscopic Polyangiitis (MPA), and other such diseases.Evaluates the presence of antineutrophil cytoplasmic antibodies (ANCA-C) in the body responsible for causing autoimmune vasculitis. ANCA-C attacks proteinase-3 of neutrophils (a type of white blood cell), leading to inflammation and swelling of the blood vessels.
How long will the reports take?
You will get the reports within 3 days after the collection of the blood sample.
What is the cost of the ANCA - PR3 (Serin Proteinase 3 antibodies) test ?
The cost of the ANCA - PR3 (Serin Proteinase 3 antibodies) test is Rs. 2500.
How often should I get tested for the ANCA - PR3 (Serin Proteinase 3 antibodies) test?
ANCA - PR3 (Serin Proteinase 3 antibodies) test is prescribed by your doctor after completing the assessment of your condition.
What are the normal values for the ANCA - PR3 (Serin Proteinase 3 antibodies) test?
Positive / Negative
What is the type of sample required?
This test requires a blood sample.
What time should I get the test done?
This test can be taken at any time during the day.
Is fasting required for an ANCA - PR3 (Serin Proteinase 3 antibodies) test?
Fasting is not required for this test.
Any other precautions to be taken before getting myself tested for an ANCA - PR3 (Serin Proteinase 3 antibodies) test?
There are no specific precautions for this test.
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